Perri is a distinguished journalist and public health advocate. She is currently co-directing and co-producing a "Conversation" series on race with The New York Times Op-Docs. She co-directed and co-produced the documentaries, "Remembering the Artist Robert De Niro, Sr." (Sundance Film Festival; HBO) and “The Education of Dee Dee Ricks” (HBO). Perri executive produced “A Journey of a Thousand Miles: Peacekeepers,” which premiered at the 2015 Toronto International Film Festival. Perri is currently in production on a film about alcoholism in the U.S. for HBO.
Perri hosts two radio shows on the SiriusXM Network: “The Perri Peltz Show” and "Doctor Radio Reports.” Her earlier work as a television news journalist includes serving as a reporter and anchor for WNBC, a contributor for NBC’s “Dateline,” an anchor at MSNBC, a news correspondent for ABC’s “20/20,” and an anchor for CNN.